We welcome Ewa Szula to the group as a new PhD student working on the metabolic profiling of mammalian cells.
Welcome Kat!
We welcome Katherine Hollywood to the group as a post-doctoral researcher. Kat will be working on the application of single cell metabolite profiling to optimisation of stem cell bioprocessing as part of a collaboration with Alan Dickson, Karen Cosgrove, Mark Dunne and Roy Goodacre.
Paper – Peptide characterisation using Argon clusters
Publication:
Peptide structural analysis using continuous Ar cluster and C60 ion beams
Satoka Aoyagi, John S. Fletcher, Sadia Sheraz (Rabbani), Tomoko Kawashima, Irma Berrueta Razo, Alex Henderson, Nicholas P. Lockyer, John C. Vickerman
Analytical and Bioanalytical Chemistry (2013) doi: 10.1007/s00216-013-7139-z
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Welcome Huriyyah!
We welcome Huriyyah Alturaifi to the group as a new PhD student working on polyatomic SIMS.
John Vickerman: A Celebration of a Career in SIMS
In 2013, John celebrates his 70th birthday. To mark this occasion, and a career devoted to the development of secondary ion mass spectrometry – including instrumentation, theory and applications – we invite you to a special scientific meeting on October 11 in the Manchester Institute of Biotechnology.
We are delighted to have an international programme of outstanding quality, with confirmed contributions from the following speakers:
- David Castner (University of Washington)
- Arnaud Delcorte (Universite Catholique de Louvain)
- Barbara Garrison (Pennsylvania State University)
- Ian Gilmore (National Physical Laboratory)
- Ron Heeren (FOM-AMOLF, The Netherlands)
- Nick Lockyer (University of Manchester)
- Nick Winograd (Pennsylvania State University)
There will be a celebration dinner and we hope that as many attendees as possible will be able to join us for that.
Registration for the meeting is available here: http://www.massspecmanchester.org/symposia/registration/
Please mark October 11 in your diaries! If you have any questions, please contact Graham Leggett (graham.leggett@sheffield.ac.uk) or Nick Lockyer (nick.lockyer@manchester.ac.uk).
Further information can be found on the MassSpectrometry@Manchester site.
Michael Barber Centre for Mass Spectrometry
Nick has taken over as Acting Director of the Michael Barber Centre for Mass Spectrometry
Paper – Water cluster primary beams
Enhancing Secondary Ion Yields in Time of Flight-Secondary Ion Mass Spectrometry Using Water Cluster Primary Beams
Sadia Sheraz née Rabbani, Andrew Barber, John S. Fletcher, Nicholas P. Lockyer, and John C. Vickerman
Analytical Chemistry 85(12) (2013) 5654–5658 doi: 10.1021/ac4013732
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SIMS and Pharmacy talk
Nick gave an invited talk on Imaging Biosystems using Secondary Ion Mass Spectrometry to industrialists and academics at the Royal Society of Chemistry in London, organised by the Joint Pharmaceutical Analysis Group and The Drug Metabolism Discussion Group. The title of the meeting was ‘New approaches in bioanalysis and analytical toxicology’.
Travel award for Jo
Jo has been awarded a bursary from the Royal Society of Chemistry towards her attendance at an international conference.
At the meeting she will present her results on mammalian cell characterization. This is part of her PhD project on Lipidomic and Metabolomic Imaging of Biological Response Mechanisms in Tissues and Single Cells involving Raman and IR spectroscopies in addition to LC-MS and SIMS analyses.
Analytical Chemistry cover art
The issue of Analytical Chemistry containing John and John’s review on Secondary Ion Mass Spectrometry: Characterizing Complex Samples in Two and Three Dimensions has artwork generated by John Fletcher on the cover.
Paper – Challenges of ToFSIMS for metabolomics
Publication:
Evaluating the challenges associated with time-of-flight secondary ion mass spectrometry for metabolomics using pure and mixed metabolites
John S. Fletcher, Helen L. Kotze, Emily G. Armitage, Nicholas P. Lockyer, John C. Vickerman
Metabolomics (2012) doi: 10.1007/s11306-012-0487-4 (2012)
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Paper – Imaging of metabolites
Publication:
Imaging of metabolites using secondary ion mass spectrometry
Emily G. Armitage, Helen L. Kotze, Nicholas P. Lockyer
Metabolomics 9 (2013) 102-109
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Funding for novel ion beams
John and Nick have been awarded funding from EPSRC to develop novel ion beam systems. The funding, £261k, is over a two year period.
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Review – SIMS of complex samples
Review:
Secondary Ion Mass Spectrometry: Characterising complex samples in two and three dimensions.
John Stephen Fletcher and John C. Vickerman
Analytical Chemistry 85 (2013) 610-639. doi: 10.1021/ac303088m
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Paper – Problems with transflection-mode IR
New publication…
The inherent problem of transflection-mode infrared spectroscopic microscopy and the ramifications for biomedical single point and imaging applications
Paul Bassan, Joe Lee, Ashwin Sachdeva, Juliana Pissardini, Konrad M. Dorling, John S. Fletcher, Alex Henderson and Peter Gardner
Analyst (2012)