Publication:
Prospect of increasing secondary ion yields in ToF-SIMS using water cluster primary ion beams
S. Sheraz (née Rabbani), A. Barber, I. Berrueta Razo, J. S. Fletcher, N.P. Lockyer and J. C. Vickerman
Surf. Interface Anal. (2014)
Paper – C60 and H2O clusters for tissue analysis
Publication (open access):
Comparing C60+ and (H2O)n+ clusters for mouse brain tissue analysis
Irma Berrueta Razo, Sadia Sheraz, Alex Henderson, Nicholas P. Lockyer and John C. Vickerman
Surf. Interface Anal. (2014)
Paper – Lipid profiling of frog embryos
Publication (open access):
Spatiotemporal lipid profiling during early embryo development of Xenopus laevis using dynamic Time-of-Flight Secondary Ion Mass Spectrometry (ToF-SIMS) Imaging
Hua Tian, John S. Fletcher, Raphael Thuret, Alex Henderson, Nancy Papalopulu, John C. Vickerman and Nicholas P. Lockyer
Journal of Lipid Research (2014)
Dr Jimmy Moore
Congratulations to Jimmy on gaining his PhD in Computational Approaches for the Interpretation of ToF-SIMS Data!
Well done!
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Paper – Suppression effects in SNMS
Publication:
Quantitative Surface Analysis of a Binary Drug Mixture—Suppression Effects in the Detection of Sputtered Ions and Post-Ionized Neutrals
Gabriel Karras, Nicholas P. Lockyer
Journal of The American Society for Mass Spectrometry (2014)
“It’s good, but it’s not right!…” How to validate your model
Alex gave a presentation entitled “It’s good, but it’s not right!…” How to validate your model at the UK Surface Analysis Forum‘s (UKSAF) Workshop on Multivariate Analysis held at the University of Nottingham, 8 January 2014.
The purpose of the workshop was to introduce users of surface analysis technologies to multivariate analysis with a combination of theory and demonstration.
The presentation covered validation of multivariate models, how to get the most out of them and how to avoid various pitfalls in the data treatment. The slides for the talk can be found here.
Awards winning poster!
At the recent SciX Conference in Milwaukee USA, Jo walked away with not one, but two awards for best poster! Both the Society for Applied Spectroscopy (SAS) and the Federation of Analytical Chemistry and Spectroscopy Societies (FACSS) judged Jo’s work on “ToF-SIMS and Raman microspectroscopy as tools for probing lipid saturation in acute myeloid leukaemia cells treated with a novel combination therapy” to be outstanding and awarded her certificates and cash.
We are very grateful to the Royal Society of Chemistry, Manchester & District Local Section for sponsoring Jo’s travel to the conference.
Welcome Ewa!
We welcome Ewa Szula to the group as a new PhD student working on the metabolic profiling of mammalian cells.
Welcome Kat!
We welcome Katherine Hollywood to the group as a post-doctoral researcher. Kat will be working on the application of single cell metabolite profiling to optimisation of stem cell bioprocessing as part of a collaboration with Alan Dickson, Karen Cosgrove, Mark Dunne and Roy Goodacre.
Paper – Peptide characterisation using Argon clusters
Publication:
Peptide structural analysis using continuous Ar cluster and C60 ion beams
Satoka Aoyagi, John S. Fletcher, Sadia Sheraz (Rabbani), Tomoko Kawashima, Irma Berrueta Razo, Alex Henderson, Nicholas P. Lockyer, John C. Vickerman
Analytical and Bioanalytical Chemistry (2013) doi: 10.1007/s00216-013-7139-z
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Welcome Huriyyah!
We welcome Huriyyah Alturaifi to the group as a new PhD student working on polyatomic SIMS.
John Vickerman: A Celebration of a Career in SIMS
In 2013, John celebrates his 70th birthday. To mark this occasion, and a career devoted to the development of secondary ion mass spectrometry – including instrumentation, theory and applications – we invite you to a special scientific meeting on October 11 in the Manchester Institute of Biotechnology.
We are delighted to have an international programme of outstanding quality, with confirmed contributions from the following speakers:
- David Castner (University of Washington)
- Arnaud Delcorte (Universite Catholique de Louvain)
- Barbara Garrison (Pennsylvania State University)
- Ian Gilmore (National Physical Laboratory)
- Ron Heeren (FOM-AMOLF, The Netherlands)
- Nick Lockyer (University of Manchester)
- Nick Winograd (Pennsylvania State University)
There will be a celebration dinner and we hope that as many attendees as possible will be able to join us for that.
Registration for the meeting is available here: http://www.massspecmanchester.org/symposia/registration/
Please mark October 11 in your diaries! If you have any questions, please contact Graham Leggett (graham.leggett@sheffield.ac.uk) or Nick Lockyer (nick.lockyer@manchester.ac.uk).
Further information can be found on the MassSpectrometry@Manchester site.
Michael Barber Centre for Mass Spectrometry
Nick has taken over as Acting Director of the Michael Barber Centre for Mass Spectrometry
Paper – Water cluster primary beams
Publication (open access):
Enhancing Secondary Ion Yields in Time of Flight-Secondary Ion Mass Spectrometry Using Water Cluster Primary Beams
Sadia Sheraz née Rabbani, Andrew Barber, John S. Fletcher, Nicholas P. Lockyer, and John C. Vickerman
Analytical Chemistry 85(12) (2013) 5654–5658 doi: 10.1021/ac4013732
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SIMS and Pharmacy talk
Nick gave an invited talk on Imaging Biosystems using Secondary Ion Mass Spectrometry to industrialists and academics at the Royal Society of Chemistry in London, organised by the Joint Pharmaceutical Analysis Group and The Drug Metabolism Discussion Group. The title of the meeting was ‘New approaches in bioanalysis and analytical toxicology’.