Lecture tour:
Following his award of the RSC Theophilus Redwood prize, John began his lecture tour with a presentation at the University of Warwick entitled,
“Is 2D and 3D mass spectral molecular imaging with sub-micron resolution a realistic prospect?”
Paper – omega-6
Publication:
Influence of omega-6 PUFA arachidonic acid and bone marrow adipocytes on metastatic spread from prostate cancer.
Brown, M. D.; Hart, C.; Gazi, E.; Gardner, P.; Lockyer, N.; Clarke, N.
Br. J. Cancer 102 (2010) 403-413 [go there now…]
Paper – Delay Line Detector
Publication:
C60+ Secondary Ion Microscopy Using a Delay Line Detector.
Klerk, Leendert A.; Lockyer, Nicholas P.; Kharchenko, Andriy; MacAleese, Luke; Dankers, Patricia Y. W.; Vickerman, John C.; Heeren, Ron M. A.
Analytical Chemistry 82 (2010) 801–807 [go there now…]
Paper – metastatic prostate cancer.
Publication:
A FTIR microspectroscopic study of the uptake and metabolism of isotopically labelled fatty acids by metastatic prostate cancer.
Gazi, E.; Harvey, T. J.; Brown, M. D.; Lockyer, N. P.; Gardner, P.; Clarke, N. W.
Vib. Spectrosc. 50 (2009) 99-105 [go there now…]
Review – 3D imaging
Review article:
Developments in molecular SIMS depth profiling and 3D imaging of biological systems using polyatomic primary ions
John S. Fletcher, Nicholas P. Lockyer, John C. Vickerman
Mass Spectrometry Reviews (2010) [go there now…]
Barbara and Nick
We welcome back Professors Barbara Garrison and Nick Winograd for another winter sabbatical. Barbara and Nick, both from Penn State University, will be with us for two months.
Matt leaves
Matt leaves us to join the research team at Porton Down. Matt has been part of SARC for 6 years, most recently visiting Berlin and Harvard as part of his post doctoral fellowship. We wish him well in his new role.
Paper – Water Ice
Publication:
A Comparative Study of Secondary Ion Emission from Water Ice under Ion Bombardment by Au+, Au3+, and C60+
Xavier A. Conlan, John S. Fletcher, Nicholas P. Lockyer and John C. Vickerman
J. Phys. Chem. C (2009) [go there now…]
Danish Mass Spec Society
The Danish Society for Mass Spectrometry have invited John F to give a keynote talk at their forthcoming annual meeting. [More…]
New research students
Once more the group expands with the addition of four new PhD students. Helen, Emily, Gareth and Jimmy will be developing our research into cancer mimics, instrumentation and computation.
SIMSXVII
A number of the group attended the 17th International Conference on Secondary Ion Mass Spectrometry (SIMS XVII) in Toronto. John F, Sadia, Ed and Alan all gave oral presentations with Alan and Ed also presenting posters.
Review – Cellular imaging
Review article:
Cellular imaging with secondary ion mass spectrometry
John S. Fletcher
Analyst 134 (2009) 2204-2215 [go there now…]
Paper – multivariate analysis
Publication:
Explanatory multivariate analysis of ToF-SIMS spectra for the discrimination of bacterial isolates
Seetharaman Vaidyanathan, John S. Fletcher, Roger M. Jarvis, Alex Henderson, Nicholas P. Lockyer, Royston Goodacre and John C. Vickerman
Analyst 134 (2009) 2352-2360 [go there now…]
Paper – molecular imaging
Review article:
A new SIMS paradigm for 2D and 3D molecular imaging of bio-systems
John S. Fletcher and John C. Vickerman
Anal. Bioanal. Chem. 396 (2010) 85-104 [go there now…]
Paper – PCA and MAF
Publication:
A comparison of PCA and MAF for ToF-SIMS image interpretation
Alex Henderson, John S. Fletcher, John C. Vickerman
Surf. Interface Anal. 41 (2009) 666-674 [go there now…]