Publication:
Effects of Cryogenic Sample Analysis on Molecular Depth Profiles with TOF-Secondary Ion Mass Spectrometry
Alan M. Piwowar, John S. Fletcher, Jeanette Kordys, Nicholas P. Lockyer, Nicholas Winograd, and John C. Vickerman
Analytical Chemistry (2010) [go there now…]
Paper – Phenotypic profiling
Publication:
Phenotypic profiling of keloid scars using FT-IR microspectroscopy reveals a unique spectral signature
Katherine A. Hollywood, Marlies Maatje, Iqbal T. Shadi, Alex Henderson, Duncan Angus McGrouther, Royston Goodacre and Ardeshir Bayat
Archives of Dermatological Research (2010) [go there now…]
Papers from SIMSXVII published
The contributions presented at the International SIMS Conference in Toronto (SIMS XVII) have now been published.
| Insight into the swelling mechanism involved in the recovery of serial numbers erased from polymer surfaces Xavier A. Conlan, Matthew J. Baker, Richard Krieg, Nicholas P. Lockyer, John C. Vickerman, Neil W. Barnett and Kieran F. Lim Surf. Interface Anal. (2010) [go there now…] |
| A new time-of-flight SIMS instrument for 3D imaging and analysis Rowland Hill, Paul Blenkinsopp, Stephen Thompson, John Vickerman and John S. Fletcher Surf. Interface Anal. (2010) [go there now…] |
| Exploring subcellular imaging on the buncher-ToF J105 3D chemical imager S. Rabbani, J. S. Fletcher, N. P. Lockyer and J. C. Vickerman Surf. Interface Anal. (2010) [go there now…] |
| A molecular dynamics study of a 5 keV C60 fullerene impact on a two-component organic molecular sample M. G. Ponomarev, B. J. Garrison, J. C. Vickerman and R. P. Webb Surf. Interface Anal. (2010) [go there now…] |
| Top-down approach to studying biological components using ToF-SIMS Alan Piwowar, John Fletcher, Nicholas Lockyer and John Vickerman Surf. Interface Anal. (2010) [go there now…] |
| Investigating the effect of temperature on depth profiles of biological material using ToF-SIMS Alan Piwowar, John Fletcher, Nicholas Lockyer and John Vickerman Surf. Interface Anal. (2010) [go there now…] |
| The effect of the H:C ratio on the sputtering of molecular solids by fullerenes Roger P. Webb, Barbara J. Garrison and John C. Vickerman Surf. Interface Anal. (2010) [go there now…] |
| Interactive spatio-spectral analysis of three-dimensional mass-spectral (3DxMS) chemical images Stephen E. Reichenbach, Xue Tian, Robert Lindquist, Qingping Tao, Alex Henderson and John C. Vickerman Surf. Interface Anal. (2010) [go there now…] |
| Molecular SIMS imaging; spatial resolution and molecular sensitivity: have we reached the end of the road? Is there light at the end of the tunnel? John S. Fletcher, Nicholas P. Lockyer and John C. Vickerman Surf. Interface Anal. (2010) [go there now…] |
| A systematic evaluation of cytospinning as a novel technique for the preparation of cells for ToF-SIMS analysis E. R. J. Jackson, J. C. Vickerman and N. P. Lockyer Surf. Interface Anal. (2010) [go there now…] |
Paper – PMMA
Publication:
The role of molecular weight on the ToF-SIMS spectra of PMMA using Au+ and C60+ primary ions.
Piwowar, Alan M.; Vickerman, John C.
Surf. Interface Anal. 42 (2010) 1387-1392 [go there now…]
Alan leaves
Having been with us for three years Alan is moving back to his native USA. He has secured a post-doctoral position in Nick Winograd’s lab at Penn State University. Since Nick is a close collaborator of ours we expect to be working closely with Alan in the future.
Theophilus Redwood Award 2009
Recognition
John Vickerman has been awarded the prestigous Theophilus Redwood Award 2009 by the Royal Society of Chemistry.
“Awarded for his outstanding contribution to the development and application of secondary ion mass spectrometry techniques for surface analysis and 3D chemical imaging of organic and biological systems.”
IUVSTA-59
Both John F and Alex presented work at the 59th IUVSTA Workshop on Surface Chemical Analysis – Improving data interpretation by multivariate & informatics techniques, in Trinidad.
Most accessed article
Recognition:
The Journal of Biophotonics list Classification of fixed urological cells using Raman tweezers on which Alex is a co-author, as one of their most accessed articles of 2009-10. See here for the listing and here to download the paper (free).
Theophilus Redwood Lecture Tour
Lecture tour:
Following his award of the RSC Theophilus Redwood prize, John began his lecture tour with a presentation at the University of Warwick entitled,
“Is 2D and 3D mass spectral molecular imaging with sub-micron resolution a realistic prospect?”
Paper – omega-6
Publication:
Influence of omega-6 PUFA arachidonic acid and bone marrow adipocytes on metastatic spread from prostate cancer.
Brown, M. D.; Hart, C.; Gazi, E.; Gardner, P.; Lockyer, N.; Clarke, N.
Br. J. Cancer 102 (2010) 403-413 [go there now…]
Paper – Delay Line Detector
Publication:
C60+ Secondary Ion Microscopy Using a Delay Line Detector.
Klerk, Leendert A.; Lockyer, Nicholas P.; Kharchenko, Andriy; MacAleese, Luke; Dankers, Patricia Y. W.; Vickerman, John C.; Heeren, Ron M. A.
Analytical Chemistry 82 (2010) 801–807 [go there now…]
Paper – metastatic prostate cancer.
Publication:
A FTIR microspectroscopic study of the uptake and metabolism of isotopically labelled fatty acids by metastatic prostate cancer.
Gazi, E.; Harvey, T. J.; Brown, M. D.; Lockyer, N. P.; Gardner, P.; Clarke, N. W.
Vib. Spectrosc. 50 (2009) 99-105 [go there now…]
Review – 3D imaging
Review article:
Developments in molecular SIMS depth profiling and 3D imaging of biological systems using polyatomic primary ions
John S. Fletcher, Nicholas P. Lockyer, John C. Vickerman
Mass Spectrometry Reviews (2010) [go there now…]
Barbara and Nick
We welcome back Professors Barbara Garrison and Nick Winograd for another winter sabbatical. Barbara and Nick, both from Penn State University, will be with us for two months.
Matt leaves
Matt leaves us to join the research team at Porton Down. Matt has been part of SARC for 6 years, most recently visiting Berlin and Harvard as part of his post doctoral fellowship. We wish him well in his new role.