Review article:
A new SIMS paradigm for 2D and 3D molecular imaging of bio-systems
John S. Fletcher and John C. Vickerman
Anal. Bioanal. Chem. 396 (2010) 85-104 [go there now…]
Paper – PCA and MAF
Publication:
A comparison of PCA and MAF for ToF-SIMS image interpretation
Alex Henderson, John S. Fletcher, John C. Vickerman
Surf. Interface Anal. 41 (2009) 666-674 [go there now…]
Funding – A new dynamic in mass spectral imaging for biological systems
Funding:
A new dynamic in mass spectral imaging for biological systems
PI: John C. Vickerman, CoI: Nick Lockyer, ResearchCoI: John S. Fletcher
£740k, June 2009 – May 2012. [EPSRC award: EP/G045623/1, more information …]
EPSRC have approved funding for a three year project to investigate 3D SIMS depth information and ionisation effects. This will fund two PDRAs and two PhD students and allows us to further strengthen our collaboration with Professors Nick Winograd (Penn State) and Stephen Reichenbach (University of Nebraska-Lincoln).
Paper – FTIR microspectroscopy
New publication:
Factors influencing the discrimination and classification of prostate cancer cell lines by FTIR microspectroscopy
T.J. Harvey, E. Gazi, A. Henderson, R.D. Snook, N.W. Clarke, M. Brown and P. Gardner
Analyst 134 (2009) 1083 – 1091 [go there now…]
Book – Surface Analysis
New book:
Surface Analysis — The Principal Techniques
Edited by John C. Vickerman and Ian S. Gilmore
Second edition, ISBN: 978-0-470-01764-7 or 978-0-470-01763-0
The second edition of this popular reference text on Surface Analysis has now been released. [go there now…]
Paper – Efficient encoding
New publication:
Efficient encoding and rapid decoding for interactive visualization of large three-dimensional hyperspectral chemical images
Stephen E. Reichenbach, Alex Henderson, Robert Lindquist, Qingping Tao
Rapid Communications in Mass Spectrometry 23 (2009) 1229–1233 [go there now…]
Paper – Internal Energy
New publication:
Internal Energy of Molecules Ejected Due to Energetic C60 Bombardment
Barbara J. Garrison, Zbigniew Postawa, Kathleen E. Ryan, John C. Vickerman, Roger P. Webb and Nicholas Winograd
Analytical Chemistry 81 (2009) 2260–2267 [go there now…]
Paper – FTIR histopathology
New publication:
Investigating FTIR based histopathology for the diagnosis of prostate cancer
Matthew J. Baker, Ehsan Gazi, Michael D. Brown, Jonathan H. Shanks, Noel W. Clarke, Peter Gardner
Journal of Biophotonics 2 (2009) 104-113 [go there now…]
EASIM
Alex presented the work of the group with a ‘multivariate analysis of images’ slant to the second European Association for Spectral Imaging (EASIM) meeting in Gembloux, Belgium.
Paper – Salt Effects
New publication:
Salt Effects on Ion Formation in Desorption Mass Spectrometry: An Investigation into the Role of Alkali Chlorides on Peak Suppression in Time-of-Flight-Secondary Ion Mass Spectrometry.
Piwowar, Alan M.; Lockyer, Nick P.; Vickerman, John C.
Analytical Chemistry 81 (2009) 1040-1048 [go there now…]
Gerhard Ertl
New publication:
In tribute to Gerhard Ertl who was awarded the 2007 Nobel Prize in Chemistry “for his studies of chemical processes on solid surfaces”
Molecular SIMS – A Journey from Single Crystal to Biological Surface Studies
John C. Vickerman
Surface Science 603 (2009) 1926-1936 [go there now…]
Most cited articles
Recognition:
The American Chemical Society have informed us that our paper on TOF-SIMS 3D Biomolecular Imaging of Xenopus laevis Oocytes Using Buckminsterfullerene (C60) Primary Ions by John (F), Nick, Raman and John (V), is one of the most cited articles published in their journal Analytical Chemistry in 2007. See here for the listing and here to download the paper.
Ionoptika J105 3D Chemical Imager
We are please to announce the arrival of our new instrument – the Ionoptika J105 3D Chemical Imager. This ToF spectrometer incorporates revolutionary technology which we hope will allow us to take large steps in the advancement of the understanding of the SIMS process and applications.
Chemical Biology Research Articles
Recognition:
Our recent article on Discrimination of Prostate Cancer Cells and Non-malignant Cells using Secondary Ion Mass Spectrometry, published in The Analyst and presenting some work by Matt and Ehsan, has been selected for inclusion in the Royal Society of Chemistry’s Chemical Biology Research Articles virtual journal. This virtual journal brings together all chemical biology literature from more than 15 RSC journals in order to raise its visibility and profile in the chemical biology community.
Enhancing new developments in ToF-SIMS through researcher exchanges
New funding:
Enhancing new developments in ToF-SIMS through researcher exchanges
We have been successful in securing EPSRC funds to bring expert researchers to Manchester and to send some of our group to the USA and The Netherlands. Later this year we will be hosting Professor Stephen Reichenbach from Nebraska University for three months and we will also be welcoming back Professors Nick Winograd and Barbara Garrison from Penn State University. Alex will be travelling to Nebraska next year and John (F) will be exchanging with a colleague from Professor Ron Heeren‘s group in Amsterdam. There is also funding for Professor Roger Webb of Surrey University to visit Penn State. [EPSRC award: EP/F012985/1, more information …]