Spatiotemporal lipid profiling during early embryo development of Xenopus laevis using dynamic Time-of-Flight Secondary Ion Mass Spectrometry (ToF-SIMS) Imaging
Hua Tian, John S. Fletcher, Raphael Thuret, Alex Henderson, Nancy Papalopulu, John C. Vickerman and Nicholas P. Lockyer
Journal of Lipid Research (2014)
Category Archives: Publications
Paper – Suppression effects in SNMS
Publication:
Quantitative Surface Analysis of a Binary Drug Mixture—Suppression Effects in the Detection of Sputtered Ions and Post-Ionized Neutrals
Gabriel Karras, Nicholas P. Lockyer
Journal of The American Society for Mass Spectrometry (2014)
Paper – Peptide characterisation using Argon clusters
Publication:
Peptide structural analysis using continuous Ar cluster and C60 ion beams
Satoka Aoyagi, John S. Fletcher, Sadia Sheraz (Rabbani), Tomoko Kawashima, Irma Berrueta Razo, Alex Henderson, Nicholas P. Lockyer, John C. Vickerman
Analytical and Bioanalytical Chemistry (2013) doi: 10.1007/s00216-013-7139-z
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Paper – Water cluster primary beams
Enhancing Secondary Ion Yields in Time of Flight-Secondary Ion Mass Spectrometry Using Water Cluster Primary Beams
Sadia Sheraz née Rabbani, Andrew Barber, John S. Fletcher, Nicholas P. Lockyer, and John C. Vickerman
Analytical Chemistry 85(12) (2013) 5654–5658 doi: 10.1021/ac4013732
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Analytical Chemistry cover art
The issue of Analytical Chemistry containing John and John’s review on Secondary Ion Mass Spectrometry: Characterizing Complex Samples in Two and Three Dimensions has artwork generated by John Fletcher on the cover.
Paper – Challenges of ToFSIMS for metabolomics
Publication:
Evaluating the challenges associated with time-of-flight secondary ion mass spectrometry for metabolomics using pure and mixed metabolites
John S. Fletcher, Helen L. Kotze, Emily G. Armitage, Nicholas P. Lockyer, John C. Vickerman
Metabolomics (2012) doi: 10.1007/s11306-012-0487-4 (2012)
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Paper – Imaging of metabolites
Publication:
Imaging of metabolites using secondary ion mass spectrometry
Emily G. Armitage, Helen L. Kotze, Nicholas P. Lockyer
Metabolomics 9 (2013) 102-109
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Review – SIMS of complex samples
Review:
Secondary Ion Mass Spectrometry: Characterising complex samples in two and three dimensions.
John Stephen Fletcher and John C. Vickerman
Analytical Chemistry 85 (2013) 610-639. doi: 10.1021/ac303088m 
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Paper – Problems with transflection-mode IR
New publication…
The inherent problem of transflection-mode infrared spectroscopic microscopy and the ramifications for biomedical single point and imaging applications
Paul Bassan, Joe Lee, Ashwin Sachdeva, Juliana Pissardini, Konrad M. Dorling, John S. Fletcher, Alex Henderson and Peter Gardner
Analyst (2012)
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Dr Emily Armitage
Congratulations to Emily on gaining her PhD in Systems Biology of HIF Metabolism in Cancer!
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Dr Helen Kotze
Congratulations to Helen on gaining her PhD in Systems biology of chemotherapy in hypoxia environments!
Paper – Metabolic profiling in cancer systems
Publication:
ToF-SIMS as a tool for metabolic profiling small biomolecules in cancer systems
Helen L. Kotze, Emily G. Armitage, John S. Fletcher, Alex Henderson, Kaye J. Williams, Nicholas P. Lockyer and John C. Vickerman
Surf. Interface Anal. doi: 10.1002/sia.5055 (2012)
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Paper – Peak picking for imaging ToFSIMS
Publication:
Peak picking as a pre-processing technique for imaging time of flight secondary ion mass spectrometry
Jimmy D. Moore, Alex Henderson, John S. Fletcher, Nicholas P. Lockyer and John C. Vickerman
Surf. Interface Anal. doi: 10.1002/sia.5062 (2012)
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Paper – SIMS Informatics
Publication:
SIMS informatics
Alex Henderson, Jimmy D. Moore and John C. Vickerman
Surf. Interface Anal. doi: 10.1002/sia.5065 (2012)
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Paper – Unlocking the hypoxic properties of cancer
Publication:
Time‐of‐flight SIMS as a novel approach to unlocking the hypoxic properties of cancer
Emily G Armitage, Helen L Kotze, John S Fletcher, Alex Henderson, Kaye J Williams, Nicholas P Lockyer, John C Vickerman
Surf. Interface Anal. doi: 10.1002/sia.5050 (2012)
