Publications by Nick Lockyer

108 The influence of polyatomic primary ion chemistry on matrix effects in secondary ion mass spectrometry analysis
Afnan M. Alnajeebi, John C. Vickerman and Nicholas P. Lockyer
Rapid Communications in Mass Spectrometry 32 (2018) 1962-1970
107 Probing the action of a novel anti-leukaemic drug therapy at the single cell level using modern vibrational spectroscopy techniques
Joanna L. Denbigh, David Perez-Guaita, Robbin R. Vernooij, Mark J. Tobin, Keith R. Bambery, Yun Xu, Andrew D. Southam, Farhat L. Khanim, Mark T. Drayson, Nicholas P. Lockyer, Royston Goodacre & Bayden R. Wood
Scientific Reports 7 (2017) 2649
106 Quartz Crystal Microbalance Assay of Clinical Calcinosis Samples and Their Synthetic Models Differentiates the Efficacy of Chelation-Based Treatments
Fan Fei, Andrzej Gallas, Yun-Chuan Chang, Yikun Rao, Alan Christy Hunter, Richard E. P. Winpenny, Ariane L. Herrick, Nicholas P. Lockyer and Christopher F. Blanford
ACS Appl. Mater. Interfaces 9 (2017) 27544–27552
105 Fossilization of melanosomes via sulfurization
Maria E. McNamara, Bart E. van Dongen, Nick P. Lockyer, Ian D. Bull and Patrick J. Orr
Palaeontology 59 (2016) 337-350
104 Matrix effects in biological SIMS using cluster ion beams of different chemical composition
Afnan M. Alnajeebi, John C. Vickerman and Nicholas P. Lockyer
Biointerphases 11 (2016) 02A317
103 Peptide Fragmentation and Surface Structural Analysis by Means of ToF-SIMS Using Large Cluster Ion Sources
Yuta Yokoyama, Satoka Aoyagi, Makiko Fujii, Jiro Matsuo, John S. Fletcher, Nicholas P. Lockyer, John C. Vickerman, Melissa K. Passarelli, Rasmus Havelund and Martin P. Seah
Analytical Chemistry 88 (2016) 3592–3597
102 Evaluation of biomolecular distributions in rat brain tissues by means of ToF-SIMS using a continuous beam of Ar clusters
Shusuke Nakano, Yuta Yokoyama, Satoka Aoyagi, Naoyuki Himi, John S. Fletcher, Nicholas P. Lockyer, Alex Henderson and John C. Vickerman
Biointerphases 11 (2016) 02A307
101 SIMS Matrix Effects of Biological Molecules under Cluster Ion Beam Bombardment
Afnan M. Alnajeebi, Sadia Sheraz née Rabbani, John C. Vickerman and Nicholas P. Lockyer
Proceedings of the Eighth Saudi Students Conference in the UK (2015) 437-444
100 Mass spectrometric imaging of brain tissue by time-of-flight secondary ion mass spectrometry – How do polyatomic primary beams C60+, Ar2000+, water-doped Ar2000+ and (H2O)6000+ compare?
Irma Berrueta Razo, Sadia Sheraz (née Rabbani), Alex Henderson, Nicholas P. Lockyer and John C. Vickerman
Rapid Commun. Mass Spectrom. 29 (2015) 1851–1862
99 Enhancing Ion Yields in TOF-SIMS - A Comparative Study of Argon and Water Cluster Primary Beams
Sadia Sheraz, Irma Berrueta Razo, Taylor P. Kohn, Nicholas P. Lockyer, and John C. Vickerman
Analytical Chemistry 87 (2015) 2367–2374
98 ToF-SIMS as tool for profiling lipids in cancer and other diseases
J.L. Denbigh and N.P. Lockyer
Materials Science and Technology 31 (2014) 137-147
97 Prospect of increasing secondary ion yields in ToF-SIMS using water cluster primary ion beams
S. Sheraz (née Rabbani), A. Barber, I. Berrueta Razo, J. S. Fletcher, N.P. Lockyer and J. C. Vickerman
Surf. Interface Anal. 46 (2014) 51–53
96 Spatiotemporal lipid profiling during early embryo development of Xenopus laevis using dynamic Time-of-Flight Secondary Ion Mass Spectrometry (ToF-SIMS) Imaging
Hua Tian, John S. Fletcher, Raphael Thuret, Alex Henderson, Nancy Papalopulu, John C. Vickerman and Nicholas P. Lockyer
Journal of Lipid Research 55 (2014) 1970-1980
95 Comparing C60+ and (H2O)n+ clusters for mouse brain tissue analysis
Irma Berrueta Razo, Sadia Sheraz, Alex Henderson, Nicholas P. Lockyer and John C. Vickerman
Surf. Interface Anal. 46 (2014) 136–139
94 Quantitative Surface Analysis of a Binary Drug Mixture—Suppression Effects in the Detection of Sputtered Ions and Post-Ionized Neutrals
Gabriel Karras, Nicholas P. Lockyer
Journal of The American Society for Mass Spectrometry 25 (2014) 832-840
93 Secondary Ion Mass Spectrometry Imaging of Biological Cells and Tissues
Nicholas P. Lockyer
in "Electron Microscopy", Ed. John Kuo, Humana Press (2014) pp 707-732
92 Laser post-ionisation for elemental and molecular analysis.
Nick Lockyer
in "TOF-SIMS: Materials Analysis by Mass Spectrometry", 2nd edition, Eds. J.C. Vickerman and D. Briggs, SurfaceSpectra, Manchester and IM Publications, Chichester (2013) 361-396
91 Peptide structural analysis using continuous Ar cluster and C60 ion beams
Satoka Aoyagi, John S. Fletcher, Sadia Sheraz (Rabbani), Tomoko Kawashima, Irma Berrueta Razo, Alex Henderson, Nicholas P. Lockyer, John C. Vickerman
Analytical and Bioanalytical Chemistry 405 (2013) 6621-6628
90 Enhancing Secondary Ion Yields in Time of Flight-Secondary Ion Mass Spectrometry Using Water Cluster Primary Beams
Sadia Sheraz née Rabbani, Andrew Barber, John S. Fletcher, Nicholas P. Lockyer, and John C. Vickerman
Analytical Chemistry 85 (2013) 5654–5658
89 Evaluating the challenges associated with time-of-flight secondary ion mass spectrometry for metabolomics using pure and mixed metabolites
John S. Fletcher, Helen L. Kotze, Emily G. Armitage, Nicholas P. Lockyer, John C. Vickerman
Metabolomics 9 (2013) 535-544
88 Imaging of metabolites using secondary ion mass spectrometry
Emily G. Armitage, Helen L. Kotze, Nicholas P. Lockyer
Metabolomics 9 (2013) 102-109
87 New prospects for molecular post-ionisation using femtosecond IR lasers
Alessia Longobardo, Alisdair N. Macpherson, John C. Vickerman, Nicholas P. Lockyer
Surf. Interface Anal. 45 (2013) 525-528
86 ToF-SIMS as a tool for metabolic profiling small biomolecules in cancer systems
Helen L. Kotze, Emily G. Armitage, John S. Fletcher, Alex Henderson, Kaye J. Williams, Nicholas P. Lockyer and John C. Vickerman
Surf. Interface Anal. 45 (2013) 277-281
85 Peak picking as a pre-processing technique for imaging time of flight secondary ion mass spectrometry
Jimmy D. Moore, Alex Henderson, John S. Fletcher, Nicholas P. Lockyer and John C. Vickerman
Surf. Interface Anal. 45 (2013) 461-465
84 Time-of-flight SIMS as a novel approach to unlocking the hypoxic properties of cancer
Emily G Armitage, Helen L Kotze, John S Fletcher, Alex Henderson, Kaye J Williams, Nicholas P Lockyer and John C Vickerman
Surf. Interface Anal. 45 (2013) 282-285
83 Comparison of C60 and GCIB primary ion beams for the analysis of cancer cells and tumour sections
John S. Fletcher, Sadia Rabbani, Andrew M. Barber, Nicholas P. Lockyer, John C. Vickerman
Surf. Interface Anal. 45 (2013) 273-276
82 The Birmingham Boron Neutron Capture Therapy (BNCT) Project:: Developments towards Selective Internal Particle Therapy
S. Green, B. Phoenix, A.J. Mill, M. Hill, M.W. Charles, J. Thompson, B. Jones, D. Ngoga, A. Detta, N.D. James, J. Doran, N. Graham, Z. Ghani, C. Wojnecki, G. Halbert, M. Elliott, S. Ford, T.M.T. Sheehan, J. Vickerman, N. Lockyer, G. Croswell, A. Boddy, A. King, G.S. Cruickshank
Clinical Oncology 23 (2011) S23–S24
81 Bioimaging of elements and small molecules using MS.
Nicholas P. Lockyer
Bioanalysis 3 (2011) 1047-1051
80 TOF-SIMS with Argon Gas Cluster Ion Beams: A Comparison with C60+.
Sadia Rabbani, Andrew M. Barber, John S. Fletcher, Nicholas P. Lockyer, John C. Vickerman
Analytical Chemistry 83 (2011) 3793–3800
79 Synchrotron FTIR analysis of drug treated ovarian A2780 cells: an ability to differentiate cell response to different drugs?
Kevin R. Flower, Intisar Khalifa, Paul Bassan, Damien Demoulin, Edward Jackson, Nicholas P. Lockyer, Alan T. McGown, Philip Miles, Lisa Vaccari, Peter Gardner
Analyst 136 (2011) 498-507
78 Insight into the swelling mechanism involved in the recovery of serial numbers erased from polymer surfaces.
Xavier A. Conlan, Matthew J. Baker, Richard Krieg, Nicholas P. Lockyer, John C. Vickerman, Neil W. Barnett and Kieran F. Lim
Surf. Interface Anal. 43 (2011) 625-627
77 Molecular SIMS imaging; spatial resolution and molecular sensitivity: have we reached the end of the road? Is there light at the end of the tunnel?
John S. Fletcher, Nicholas P. Lockyer and John C. Vickerman
Surf. Interface Anal. 43 (2011) 253-256
76 Investigating the effect of temperature on depth profiles of biological material using ToF-SIMS.
Alan Piwowar, John Fletcher, Nicholas Lockyer and John Vickerman
Surf. Interface Anal. 43 (2011) 207-210
75 Top-down approach to studying biological components using ToF-SIMS.
Alan Piwowar, John Fletcher, Nicholas Lockyer and John Vickerman
Surf. Interface Anal. 43 (2011) 265-268
74 A systematic evaluation of cytospinning as a novel technique for the preparation of cells for ToF-SIMS analysis.
E. R. J. Jackson, J. C. Vickerman and N. P. Lockyer
Surf. Interface Anal. 43 (2011) 290-293
73 Exploring subcellular imaging on the buncher-ToF J105 3D chemical imager.
S. Rabbani, J. S. Fletcher, N. P. Lockyer and J. C. Vickerman
Surf. Interface Anal. 43 (2011) 380-384
72 Developments in molecular SIMS depth profiling and 3D imaging of biological systems using polyatomic primary ions.
John S. Fletcher, Nicholas P. Lockyer, John C. Vickerman
Mass Spectrom. Rev. 30 (2011) 142-174
71 Three-dimensional mass spectral imaging of HeLa-M cells - sample preparation, data interpretation and visualisation.
John S. Fletcher, Sadia Rabbani, Alex Henderson, Nicholas P. Lockyer, John C. Vickerman
Rapid Commun. Mass Spectrom. 25 (2011) 925-932
70 RMieS-EMSC correction for infrared spectra of biological cells: Extension using full Mie theory and GPU computing.
Bassan, Paul; Kohler, Achim; Martens, Harald; Lee, Joe; Jackson, Edward; Lockyer, Nicholas; Dumas, Paul; Brown, Michael; Clarke, Noel; Gardner, Peter.
J. Biophotonics 3 (2010) 609-620
69 Effects of Cryogenic Sample Analysis on Molecular Depth Profiles with TOF-Secondary Ion Mass Spectrometry.
Alan M. Piwowar, John S. Fletcher, Jeanette Kordys, Nicholas P. Lockyer, Nicholas Winograd, and John C. Vickerman
Analytical Chemistry 82 (2010) 8291-8299
68 A Comparative Study of Secondary Ion Emission from Water Ice under Ion Bombardment by Au+, Au3+, and C60+.
Xavier A. Conlan, John S. Fletcher, Nicholas P. Lockyer and John C. Vickerman
J. Phys. Chem. B 114 (2010) 5468-5479
67 C60+ Secondary Ion Microscopy Using a Delay Line Detector.
Klerk, Leendert A.; Lockyer, Nicholas P.; Kharchenko, Andriy; MacAleese, Luke; Dankers, Patricia Y. W.; Vickerman, John C.; Heeren, Ron M. A.
Analytical Chemistry 82 (2010) 801-807
66 Influence of omega-6 PUFA arachidonic acid and bone marrow adipocytes on metastatic spread from prostate cancer.
Brown, M. D.; Hart, C.; Gazi, E.; Gardner, P.; Lockyer, N.; Clarke, N.
Br. J. Cancer 102 (2010) 403-413
65 A FTIR microspectroscopic study of the uptake and metabolism of isotopically labelled fatty acids by metastatic prostate cancer.
Gazi, E.; Harvey, T. J.; Brown, M. D.; Lockyer, N. P.; Gardner, P.; Clarke, N. W.
Vib. Spectrosc. 50 (2009) 99-105
64 Explanatory multivariate analysis of ToF-SIMS spectra for the discrimination of bacterial isolates.
Seetharaman Vaidyanathan, John S. Fletcher, Roger M. Jarvis, Alex Henderson, Nicholas P. Lockyer, Royston Goodacre and John C. Vickerman
Analyst 134 (2009) 2352-2360
63 A cancer research UK pharmacokinetic study of BPA-mannitol in patients with high grade glioma to optimise uptake parameters for clinical trials of BNCT.
Cruickshank, G. S.; Ngoga, D.; Detta, A.; Green, S.; James, N. D.; Wojnecki, C.; Doran, J.; Hardie, J.; Chester, M.; Graham, N.; Ghani, Z.; Halbert, G.; Elliot, M.; Ford, S.; Braithwaite, R.; Sheehan, T. M. T.; Vickerman, J.; Lockyer, N.; Steinfeldt, H.; Croswell, G.; Chopra, A.; Sugar, R.; Boddy, A.
Appl. Radiat. Isot. 67 (2009) S31-S33
62 Salt Effects on Ion Formation in Desorption Mass Spectrometry: An Investigation into the Role of Alkali Chlorides on Peak Suppression in Time-of-Flight-Secondary Ion Mass Spectrometry.
Piwowar, Alan M.; Lockyer, Nick P.; Vickerman, John C.
Analytical Chemistry 81 (2009) 1040-1048
61 Uncovering new challenges in bio-analysis with ToF-SIMS.
John S. Fletcher, Alex Henderson, Gregory X. Biddulph, Seetharaman Vaidyanathan, Nicholas P. Lockyer and John C. Vickerman
Applied Surface Science 255 (2008) 1264-1270
60 Exploratory analysis of TOF-SIMS data from biological surfaces.
Seetharaman Vaidyanathan, John S. Fletcher, Alex Henderson, Nicholas P. Lockyer and John C. Vickerman
Applied Surface Science 255 (2008) 1599-1602
59 Substrate effects on the analysis of biomolecular layers using Au+, Au3 + and C60 + bombardments.
Jeanette Kordys, John S. Fletcher, Nicholas P. Lockyer and John C. Vickerman
Applied Surface Science 255 (2008) 890-892
58 TOF-SIMS investigation of Streptomyces coelicolor, a mycelial bacterium.
Seetharaman Vaidyanathan, John S. Fletcher, Nicholas P. Lockyer and John C. Vickerman
Applied Surface Science 255 (2008) 922-925
57 ToF-SIMS PC-DFA analysis of prostate cancer cell lines.
M.J. Baker, E. Gazi, M.D. Brown, N.W. Clarke, J.C. Vickerman and N.P. Lockyer
Applied Surface Science 255 (2008) 1084-1087
56 Investigating lipid-lipid and lipid-protein interactions in model membranes by ToF-SIMS.
L. Zheng, C.M. McQuaw, M.J. Baker, N.P. Lockyer, J.C. Vickerman, A.G. Ewing and N. Winograd
Applied Surface Science 255 (2008) 1190-1192
55 Investigation of molecular weight effects of polystyrene in ToF-SIMS using C60 + and Au+ primary ion beams.
Alan M. Piwowar, Nicholas Lockyer and John C. Vickerman
Applied Surface Science 255 (2008) 912-915
54 Mass Spectral Imaging of Glycophospholipids, Cholesterol, and Glycophorin A in Model Cell Membranes.
Matthew J. Baker, Leiliang Zheng, Nicholas Winograd, Nicholas P. Lockyer and John C. Vickerman
Langmuir 24 (2008) 11803-11810
53 A New Dynamic in Mass Spectral Imaging of Single Biological Cells.
John S. Fletcher, Sadia Rabbani, Alex Henderson, Paul Blenkinsopp, Steve P. Thompson, Nicholas P. Lockyer, and John C. Vickerman
Analytical Chemistry 80 (2008) 9058-9064
52 Discrimination of prostate cancer cells and non-malignant cells using secondary ion mass spectrometry.
Matthew J. Baker, Michael D. Brown, Ehsan Gazi, Noel W. Clarke, John C. Vickerman and Nicholas P. Lockyer
Analyst 133 (2008) 175-179
51 Depth Profiling Brain Tissue Sections with a 40 keV C60+ Primary Ion Beam.
Emrys A. Jones, Nicholas P. Lockyer, John C. Vickerman
Analytical Chemistry 80 (2008) 2125-2132
50 Subsurface Biomolecular Imaging of Streptomyces coelicolor Using Secondary Ion Mass Spectrometry.
Seetharaman Vaidyanathan, John S. Fletcher, Roy Goodacre, Nicholas P. Lockyer, Jason Micklefield, and John C. Vickerman
Analytical Chemistry 80 (2008) 1942-1951
49 Static secondary ion mass spectrometry for biological and biomedical research.
Lockyer, Nicholas P.
Methods Mol. Biol. 369 (2007) 543-567
48 Biomolecular profiling of metastatic prostate cancer cells in bone marrow tissue using FTIR microspectroscopy: a pilot study.
Gazi, E.; Dwyer, J.; Lockyer, N. P.; Gardner, P.; Shanks, J. H.; Roulson, J.; Hart, C. A.; Clarke, N. W.; Brown, M. D.
Analytical and Bioanalytical Chemistry 387 (2007) 1621-1631
47 Direct evidence of lipid translocation between adipocytes and prostate cancer cells with imaging FTIR microspectroscopy.
Gazi, Ehsan; Gardner, Peter; Lockyer, Nicholas P.; Hart, Claire A.; Brown, Michael D.; Clarke, Noel W.
Journal of Lipid Research 48 (2007) 1846-1856
46 Properties of C84 and C24H12 Molecular Ion Sources for Routine TOF-SIMS Analysis.
Biddulph, Gregory X.; Piwowar, Alan M.; Fletcher, John S.; Lockyer, Nicholas P.; Vickerman, John C.
Analytical Chemistry 79 (2007) 7259-7266
45 Suppression and Enhancement of Secondary Ion Formation Due to the Chemical Environment in Static-Secondary Ion Mass Spectrometry.
Jones, Emrys A.; Lockyer, Nicholas P.; Kordys, Jeanette; Vickerman, John C.
Journal of the American Society for Mass Spectrometry 18 (2007) 1559-1567
44 TOF-SIMS 3D Biomolecular Imaging of Xenopus laevis Oocytes Using Buckminsterfullerene (C60) Primary Ions.
Fletcher, John S.; Lockyer, Nicholas P.; Vaidyanathan, Seetharaman; Vickerman, John C.
Analytical Chemistry 79 (2007) 2199-2206
43 Mass spectral analysis and imaging of tissue by ToF-SIMS-The role of buckminsterfullerene, C60 +, primary ions.
Jones, Emrys A.; Lockyer, Nicholas P.; Vickerman, John C.
International Journal of Mass Spectrometry 260 (2007) 146-157
42 A Correlation of FTIR Spectra Derived from Prostate Cancer Biopsies with Gleason Grade and Tumour Stage
E.Gazi, M.Baker, J.Dwyer, N.P.Lockyer, P.Gardner, J.H.Shanks, R.S.Reeve, C.A.Hart. N.W.Clarke, M.D.Brown
European Urology 50 (2006) 750-761
41 TOF-SIMS Analysis Using C60. Effect of Impact Energy on Yield and Damage.
Fletcher, John S.; Conlan, Xavier A.; Jones, Emrys A.; Biddulph, Greg; Lockyer, Nicholas P.; Vickerman, John C.
Analytical Chemistry 78 (2006) 1827-1831
40 Is proton cationization promoted by polyatomic primary ion bombardment during time-of-flight secondary ion mass spectrometry analysis of frozen aqueous solutions?
Conlan, Xavier A.; Lockyer, Nicholas P.; Vickerman, John C.
Rapid Communications in Mass Spectrometry 20 (2006) 1327-1334
39 Using polyatomic primary ions to probe an amino acid and a nucleic base in water ice.
Conlan, X. A.; Biddulph, G. X.; Lockyer, N. P.; Vickerman, J. C.
Applied Surface Science 252 (2006) 6506-6508
38 Molecular depth profiling of organic and biological materials.
Fletcher, John S.; Conlan, Xavier A.; Lockyer, Nicholas P.; Vickerman, John C.
Applied Surface Science 252 (2006) 6513-6516
37 Polyethylene terephthalate (PET) bulk film analysis using C60 +, Au3 +, and Au+ primary ion beams.
Conlan, X. A.; Gilmore, I. S.; Henderson, A.; Lockyer, N. P.; Vickerman, J. C.
Applied Surface Science 252 (2006) 6562-6565
36 ToF-SIMS studies of Bacillus using multivariate analysis with possible identification and taxonomic applications.
Thompson, C. E.; Ellis, J.; Fletcher, J. S.; Goodacre, R.; Henderson, A.; Lockyer, N. P.; Vickerman, J. C.
Applied Surface Science 252 (2006) 6719-6722
35 Suppression and enhancement of non-native molecules within biological systems.
Jones, E. A.; Lockyer, N. P.; Vickerman, J. C.
Applied Surface Science 252 (2006) 6727-6730
34 A comparative study of secondary ion yield from model biological membranes using Aun+ and C60+ primary ion sources.
Baker, M. J.; Fletcher, J. S.; Jungnickel, H.; Lockyer, N. P.; Vickerman, J. C.
Applied Surface Science 252 (2006) 6731-6733
33 ToF-SIMS analysis of bio-systems: Are polyatomic primary ions the solution?
Jones, Emrys A.; Fletcher, John S.; Thompson, Charlotte E.; Jackson, Dean A.; Lockyer, Nicholas P.; Vickerman, John C.
Applied Surface Science 252 (2006) 6844-6854
32 Rapid discrimination of the causal agents of urinary tract infection using ToF-SIMS with chemometric cluster analysis.
Fletcher, John S.; Henderson, Alexander; Jarvis, Roger M.; Lockyer, Nicholas P.; Vickerman, John C.; Goodacre, Royston.
Applied Surface Science 252 (2006) 6869-6874
31 C60, Buckminsterfullerene: its impact on biological ToF-SIMS analysis.
Fletcher, John S.; Lockyer, Nicholas P.; Vickerman, John C.
Surface and Interface Analysis 38 (2006) 1393-1400
30 Fixation protocols for subcellular imaging by synchrotron-based Fourier transform infrared microspectroscopy.
Gazi, E.; Dwyer, J.; Lockyer, N. P.; Miyan, J.; Gardner, P.; Hart, C.; Brown, M.; Clarke, N. W.
Biopolymers 77 (2005) 18-30
29 Surface analysis of novel hydroxyapatite bioceramics containing titanium(IV) and fluoride.
Silwood, Christopher J. L.; Abrahams, Isaac; Apperley, David C.; Lockyer, Nicholas P.; Lynch, Edward; Motevalli, Majid; Nix, Roger M.; Grootveld, Martin.
Journal of Materials Chemistry 15 (2005) 1626-1636
28 A study of cytokinetic and motile prostate cancer cells using synchrotron-based FTIR microspectroscopic imaging.
Gazi, E.; Dwyer, J.; Lockyer, N. P.; Miyan, J.; Gardner, P.; Hart, C. A.; Brown, M. D.; Clarke, N. W.
Vibrational Spectroscopy 38 (2005) 193-201
27 Application of TOF-SIMS with Chemometrics To Discriminate between Four Different Yeast Strains from the Species Candida glabrata and Saccharomyces cerevisiae.
Jungnickel, H.; Jones, E. A.; Lockyer, N. P.; Oliver, S. G.; Stephens, G. M.; Vickerman, J. C.
Analytical Chemistry 77 (2005) 1740-1745
26 Mechanisms of secondary ion emission from self-assembled monolayers and multilayers.
Wong, Stephen C. C.; Lockyer, Nicholas P.; Vickerman, John C.
Surface and Interface Analysis 37 (2005) 721-730
25 Urban PM2.5 surface chemistry and interactions with bronchoalveolar lavage fluid.
Kendall, Michaela; Guntern, Jodok; Lockyer, Nicholas P.; Jones, Frances H.; Hutton, Bernie M.; Lippmann, Morton; Tetley, Teresa D.
Inhalation Toxicology 16 (2004) 115-129
24 C60 cluster ion bombardment of organic surfaces.
Weibel, D. E.; Lockyer, N.; Vickerman, J. C.
Applied Surface Science 231-232 (2004) 146-152
23 Progress in cellular analysis using ToF-SIMS.
Lockyer, N. P.; Vickerman, J. C.
Applied Surface Science 231-232 (2004) 377-384
22 ToF-SIMS studies as a tool to discriminate between spores and vegetative cells of bacteria.
Thompson, C. E.; Jungnickel, H.; Lockyer, N. P.; Stephens, G. M.; Vickerman, J. C.
Applied Surface Science 231-232 (2004) 420-423
21 Imaging ToF-SIMS and synchrotron-based FT-IR microspectroscopic studies of prostate cancer cell lines.
Gazi, E.; Lockyer, N. P.; Vickerman, J. C.; Gardner, P.; Dwyer, J.; Hart, C. A.; Brown, M. D.; Clarke, N. W.; Miyan, J.
Applied Surface Science 231-232 (2004) 452-456
20 Applications of Fourier transform infrared microspectroscopy in studies of benign prostate and prostate cancer. A pilot study
E Gazi, J Dwyer, P Gardner, A Ghanbari-Siahkali, AP Wade, J Miyan, NP Lockyer, JC Vickerman, NW Clarke, JH Shanks, LJ Scott, CA Hart, M Brown
Journal of Pathology 201 (2003) 99-108
19 Development of a C60+ ion gun for static SIMS and chemical imaging.
Wong, S. C. C.; Hill, R.; Blenkinsopp, P.; Lockyer, N. P.; Weibel, D. E.; Vickerman, J. C.
Applied Surface Science 203-204 (2003) 219-222
18 Development and experimental application of a gold liquid metal ion source.
Davies, N.; Weibel, D. E.; Blenkinsopp, P.; Lockyer, N.; Hill, R.; Vickerman, J. C.
Applied Surface Science 203-204 (2003) 223-227
17 Detection of chlorinated pesticides on the surface of fungus using ToF-SIMS.
Cliff, B.; Weibel, D. E.; Lockyer, N. P.; Jungnickel, H.; Stephens, G.; Vickerman, J. C.
Applied Surface Science 203-204 (2003) 710-713
16 Development of instrumentation for routine ToF-SIMS imaging analysis of biological material.
Cliff, B.; Lockyer, N. P.; Corlett, C.; Vickerman, J. C.
Applied Surface Science 203-204 (2003) 730-733
15 A C60 Primary Ion Beam System for Time of Flight Secondary Ion Mass Spectrometry: Its Development and Secondary Ion Yield Characteristics.
Weibel, Daniel; Wong, Steve; Lockyer, Nicholas; Blenkinsopp, Paul; Hill, Rowland; Vickerman, John C.
Analytical Chemistry 75 (2003) 1754-1764
14 Probing cell chemistry with time-of-flight secondary ion mass spectrometry: Development and exploitation of instrumentation for studies of frozen-hydrated biological material.
Cliff, Ben; Lockyer, Nicholas; Jungnickel, Harald; Stephens, Gill; Vickerman, John C.
Rapid Communications in Mass Spectrometry 17 (2003) 2163-2167
13 The combined application of FTIR microspectroscopy and ToF-SIMS imaging in the study of prostate cancer.
Gazi, Ehsan; Dwyer, John; Lockyer, Nicholas; Gardner, Peter; Vickerman, John C.; Miyan, Jaleel; Hart, Claire A.; Brown, Mick; Shanks, Jonathan H.; Clarke, Noel.
Faraday Discussions 126 (2003) 41-59
12 Laser post-ionisation for molecular analysis.
Lockyer, Nicholas P.
in "TOF-SIMS: Surface Analysis by Mass Spectrometry", Eds. J.C. Vickerman and D. Briggs, SurfaceSpectra, Manchester and IM Publications, Chichester (2001) 417-443
11 Halogen Concentration and Distribution in Allan Hills 84001 measured by Time-of-Flight Secondary Ion Mass Spectrometry
G. Holland, I.C. Lyon, B. Cliff, N.P. Lockyer and J.C. Vickerman
Meteoritics & Planetary Science 35 (2000) A76
10 Single photon and femtosecond multiphoton ionisation of the dipeptide valyl-valine.
Lockyer, N. P.; Vickerman, J. C.
International Journal of Mass Spectrometry 197 (2000) 197-209
9 TOF-SSIMS studies of self-assembled multilayers.
Wong, S. C. C.; Canry, J. -C.; Lockyer, N. P.; Vickerman, J. C.
Secondary Ion Mass Spectrometry, SIMS XII, Proceedings of the International Conference on Secondary Ion Mass Spectrometry, 12th, Brussels, Belgium, Sept. 5-10, 1999 (2000) 195-198
8 Surface analysis by TOF-SIMS and laser post-ionisation SNMS of ion induced modified Si oxide and Mo oxide surfaces.
Cardenas, J.; Lockyer, N. P.; Vickerman, J. C.
Secondary Ion Mass Spectrometry, SIMS XII, Proceedings of the International Conference on Secondary Ion Mass Spectrometry, 12th, Brussels, Belgium, Sept. 5-10, 1999 (2000) 429-432
7 TOFSIMS and laser post-ionization imaging of biomolecules at high spatial resolution.
Lockyer, N. P.; Vickerman, J. C.
Institute of Physics Conference Series 165 (2000) 337-338
6 Multiphoton ionization mass spectrometry of small biomolecules with nanosecond and femtosecond laser pulses.
Lockyer, N. P.; Vickerman, J. C.
International Journal of Mass Spectrometry 176 (1998) 77-86
5 Development of a biological imaging instrument.
Lockyer, N. P.; Wong, S. C. C.; Vickerman, J. C.
AIP Conference Proceedings 454 (1998) 358-363
4 Resonance Ionization Spectroscopy. (Ninth International Symposium, held in Manchester, United Kingdom, June 21-25, 1998.) [In: AIP Conf. Proc., 1998; 454].
Vickerman, John C.; Lyon, Ian; Lockyer, Nick P.; Parks, James E.; Editors.
(1998) 368 pp.
3 Photofragmentation of dipeptides using nanosecond and femtosecond lasers
N.P. Lockyer and J.C. Vickerman
Proceedings of the 10th International Conference on Secondary Ion Mass Spectrometry (1997) 783-786
2 Resonant photoionization and fragmentation of dipeptides by nanosecond and femtosecond lasers.
N.P. Lockyer and J.C. Vickerman
AIP Conference Proceedings 388 (1997) 293-296
1 Single photon ionization mass spectrometry using laser-generated vacuum ultraviolet photons.
Lockyer, Nicholas P.; Vickerman, John C.
Laser Chemistry 17 (1997) 139-159